Issue: #4 B
Let me check the Marvel Wiki. Hang on...OK...Deadpool is a guy with guns and swords...Thanos is an Eternal with strength, endurance, agility, and nearly invulnerable skin, who can shoot cosmic energy from his eyes and hands.Sounds like a fair fight!
Creators: Alan Fine, Axel Alonso, Dan Buckley, Joe Quesada, Joe Sabino, Heather Antos, Jordan D. White, Ruth Redmond, Tradd Moore, Ron Lim, Tim Seeley, Elmo Bondoc, Matt Wilson
Characters: Deadpool, Doctor Doom, Captain Universe, Thanos, Death, In-Betweener, Black Talon, Eternity
Story arcs: Deadpool vs Thanos