Adventures of Superman — DC Comics
Issue: #646
Mxy is back! Lois confronts her would-be assassin ? and she must do it alone, because Superman has his hands full with a very different Mr. Mxyzptlk! And this time Mxy's no joke!
Creators: Dan DiDio, Eddie Berganza, Dave McCaig, Rob Leigh, Karl Kerschl, Greg Rucka, Jeanine Schaefer, Richard Horie, Tanya Horie, Wayne Faucher
Characters: Superman, Lois Lane, Mr. Mxyzptlk, Barry Allen, Wonder Woman, Jimmy Olsen, Lex Luthor, Perry White, Brainiac, General Zod, Sasha Bordeaux, Lt. Lupe Leocadio, Emil Hamilton, Lana Lang, Pete Ross, Jonah McCarthy