Spider-Man's Tangled Web — Marvel
Issue: #2
The web-slinger is being pursued by a relentless foe who gives new meaning to the adage "beauty is only skin-deep"!One of Parker's high school tormenters puts various clues together. He breaks into the lab that held the radioactive spider that gave Peter Parker his spider-powers. The original spider is long dead but the bully eats it. He essentially becomes living spiders in a human suit and moves...
First appearances: Skye
Creators: Garth Ennis, Axel Alonso, Richard Starkings, Glenn Fabry, James Hodgkins, John McCrea, Steve Buccellato, Wes Abbott
Characters: Spider-Man, Skye, The Thousand, Jess Patton