Issue: #17
Patient Zero and Itsy Bitsy have been killing in Spider-Man and Deadpool's names.This has sent Spider-Man into a tailspin.Deadpool's only hope is to get to Spidey before the Friendly Neighborhood Spider-Man does something very un-friendly.
Creators: Alan Fine, Axel Alonso, Dan Buckley, Joe Quesada, Joe Sabino, Walden Wong, Jordan D. White, Nick Lowe, Ed McGuinness, Mark Morales, Manny Mederos, Devin Lewis, Allison Stock, Joe Kelly, Jason Keith, Matt Yackey
Characters: Deadpool, Spider-Man, Anna Maria Marconi, Ellie Camacho, Itsy Bitsy
Story arcs: Itsy Bitsy